Nitroimidazoles - Pharmacology - Merck Veterinary Manual.
What does nitroimidazole mean? nitroimidazole is defined by the lexicographers at Oxford Dictionaries as Any of a number of synthetic nitro-substituted imidazole derivatives, which are used as antimicrobial agents, especia.
The three most likely intermediates in the mechanism of action of 5-nitroimidazole antibiotics (the radical anions of nitroimidazoles, imidazol-5-yl radicals and 5-nitroso imidazoles) have been studied. A range of 5-nitroimidazoles have been synthesised and analysed by electron spin resonance spectroscopy, (e.s.r.) and the electron spin density of their radical anions has been determined.
Nitroimidazole antibacterial activity was first discovered in extracts from Nocardia mesenterica (Maeda et al., 1953) and Streptomyces eurocidicus (Osato et al., 1955). The active agent, called azomycin, was identified as 2-nitroimidazole ( Figure 2.3.2 ) (Nakamura et al., 1955), a metabolite produced from arginine (at least in the latter of these two bacteria) (Nakane et al., 1977).
Nitroimidazole (5-Nitro-1H-imidazole) derivatives (metronidazole, tinidazole, nimorazole, dimetridazole) are a class of antibiotic drugs used against anaerobic bacteria and protozoa infections, particularly giardiasis in people and animals. It is also commonly used with other antibiotics to treat pleuropneumonia, peritonitis, abdominal abscesses, and other severe infections caused by aerobic.
Introduction: Salmonella infection is typically associated with gastrointestinal symptoms in humans and Salmonella species may broadly be classified as typhoid-causing or non-typhoidal (Wang et al.
Obat antibiotik jika salah digunakan dapat BERBAHAYA bagi tubuh manusia. Oleh karena itu, Anda harus mengetahui dengan baik jenis dan golongan antibiotik. Artikel berikut ini akan menjelaskan jenis obat antibiotik, cara mengonsumsinya, beserta efek samping yang diberikan. Baca artikelnya sekarang juga!
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